<ESG investment indexes adopted by GPIF>

GPIF is one of the world’s largest institutional investors, managing Japan’s public pension reserve funds. To promote the sustainable growth of the overall market and enhance long-term returns, GPIF actively advances ESG investing. When selecting investment targets, GPIF adopts the following indices, which cover a wide range of themes such as general ESG factors, climate change, and human capital.

• MSCI Nihonkabu ESG Select Leaders Index (3 consecutive years from 2024)
  An index composed of companies selected from each industry within the MSCI Nihonkabu IMI Index, developed by MSCI in the United States, based on their outstanding ESG performance.
• FTSE JPX Blossom Japan Index (9 consecutive years from 2018)
  An index created by FTSE Russell, a global index provider, designed to measure the performance of companies that have taken specific actions regarding ESG.
• FTSE JPX Blossom Japan Sector Relative Index (5 consecutive years from 2022)
  An index constructed by FTSE Russell that reflects the performance of Japanese companies in each sector that demonstrate relatively strong ESG initiatives.
• S&P/JPX Carbon Efficient Index (9 consecutive years from 2018)
  This index targets stocks that make up the Tokyo Stock Price Index (TOPIX) and is composed of Japanese companies with excellent evaluations in environmental information disclosure and carbon efficiency (carbon emissions per unit of revenue).
• Morningstar Japan ex-REIT Gender Diversity Tilt Index (4 consecutive years from 2023)
  This index is composed of companies selected for their excellent evaluations in gender diversity efforts, based on research by Equileap.

<ESG investment index provided by FTSE Russell>

• FTSE4Good Index Series (9 consecutive years from 2018)
  An international index created by FTSE Russell, designed to measure the performance of companies demonstrating strong ESG practices.

Under the corporate philosophy, “Dedicated to the Fight against Disease and Pain,” Ono has been committed to addressing health challenges through the creation of innovative medicines. Ono also believes that promoting ESG-focused management is essential to remain a company that society needs.
In FY2021, Ono established its Sustainable Management Policy and is actively working to “Conserving a rich global environment for future generations,” “Realization of a society in which everyone can play an active role,” and “Establishment of highly transparent and robust management.” Going forward, Ono will continue to deliver innovative medicines to patients around the world, contribute to the realization of a sustainable society, and strive to enhance its corporate value over the medium to long term. ( https://sustainability.ono-pharma.com/en/themes/100 )